ELK Biotechnology Claudin-4 rabbit pAb
Claudin-4 rabbit polyclonal antibody로 세포 간 밀착 연결(tight junction) 단백질 검출에 적합. WB, IHC, IF, ELISA 등 다양한 응용 가능. 인체 Claudin-4 유래 펩타이드로 면역화된 고품질 항체. Human, Mouse, Rat 반응성.
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Claudin-4 rabbit pAb
공급업체: ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Claudin-4 rabbit pAb |
| Alternative Names | CLDN4; CPER; CPETR1; WBSCR8; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Claudin 4 (AA range: 160–209) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 22 kD |
| GeneID (Human) | 1364 |
| Human Swiss-Prot No | O14493 |
| Cellular Localization | Cell junction, tight junction; Cell membrane; Multi-pass membrane protein. CLDN4 is required for tight junction localization in the kidney. |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. (Provided by RefSeq, Sep 2013)
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