Thermo Fisher Scientific Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody (6E1)
인간 Thyroglobulin을 인식하는 Mouse Monoclonal Antibody(6E1)로, IHC(P), IHC(PFA), ELISA에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, PBS buffer에 보존. 갑상선 세포 마커 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.1–0.2 µg/mL |
| ELISA | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6E1 |
| Immunogen | Human thyroid follicular cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Mouse, Rat
- Others not known
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones (T4 and T3).
Thyroid disorders are largely autoimmune in origin, and anti-thyroglobulin autoantibodies were the first such factors discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves disease), with the highest levels observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer and can be used for monitoring cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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