Thermo Fisher Scientific Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody (6E1)
사람 Thyroglobulin을 인식하는 단일클론 항체로, 갑상선 세포 마커 연구에 적합합니다. IHC(P), IHC(PFA), ELISA에 사용 가능하며, 단백질 A/G로 정제된 액상 항체입니다. 인간 특이적 반응성을 가지며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.1–0.2 µg/mL |
| ELISA | 2–4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6E1 |
| Immunogen | Human thyroid follicular cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Does not react with Mouse, Rat; others not known.
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3. Thyroid disorders are largely autoimmune in origin, and anti-thyroglobulin autoantibodies were among the first factors discovered. Anti-hTG is found in all thyroid autoimmune diseases (e.g., Hashimoto thyroiditis, Graves disease), with the highest levels in Hashimoto thyroiditis. It is also characteristic of thyroid cancer and can be used for patient follow-up.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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