Thermo Fisher Scientific AHA1 Polyclonal Antibody
AHA1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 인간, 마우스, 랫트에 반응합니다. Western blot과 ELISA에 적합하며, 액상 형태로 제공됩니다. HSP90AA1의 보조 샤페론 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–338 of human AHA1 (NP_036243.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.99 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2914741 |
Product Specific Information
- Positive test controls: A-549, MCF7, 293T, Rat brain
- Subcellular localization: Cytoplasm, Endoplasmic reticulum, cytosol
Immunogen sequence:
MAKWGEGDPR WIVEERADAT NVNNWHWTER DASNWSTDKL KTLFLAVQVQ NEEGKCEVTE VSKLDGEASI NNRKGKLIFF YEWSVKLNWT GTSKSGVQYK GHVEIPNLSD ENSVDEVEIS VSLAKDEPDT NLVALMKEEG VKLLREAMGI YISTLKTEFT QGMILPTMNG ESVDPVGQPA LKTEERKAKP APSKTQARPV GVKIPTCKIT LKETFLTSPE ELYRVFTTQE LVQAFTHAPA TLEADRGGKF HMVDGNVSGE FTDLVPEKHI VMKWRFKSWP EGHFATITLT FIDKNGETEL CMEGRGIPAP EEERTRQGWQ RYYFEGIKQT FGYGARLF
Target Information
Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1, increasing its chaperone activity. Competes with inhibitory co-chaperones FNIP1 and TSC1 for binding to HSP90AA1, providing a reciprocal regulatory mechanism for chaperoning of client proteins. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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