Thermo Fisher Scientific NCALD Polyclonal Antibody
Thermo Fisher Scientific의 NCALD Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며 Rabbit IgG 기반의 비결합 항체입니다. Western blot 및 ELISA에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–193 of human NCALD (NP_114430.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.59 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914737 |
Product Specific Information
Positive test controls include:
A-549, THP-1, BT-474, Mouse brain, Mouse liver, Mouse lung, Mouse spinal cord, Rat brain.
Immunogen sequence:
MGKQNSKLRP EVMQDLLEST DFTEHEIQEW YKGFLRDCPS GHLSMEEFKK IYGNFFPYGD ASKFAEHVFR TFDANGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISKAE MLEIVQAIYK MVSSVMKMPE DESTPEKRTE KIFRQMDTNR DGKLSLEEFI RGAKSDPSIV RLLQCDPSSA GQF
Target Information
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops.
At resting calcium levels, the protein is cytosolic; however, elevated intracellular calcium induces a conformational change that exposes the myristoyl group, leading to membrane association and partial co-localization with the perinuclear trans-Golgi network.
The protein is thought to regulate G protein-coupled receptor signal transduction. Several alternatively spliced variants exist, all encoding the same protein; additional variants may exist but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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