Thermo Fisher Scientific POLR1D Polyclonal Antibody
Rabbit polyclonal antibody against human POLR1D for WB and ELISA. Recognizes POLR1D involved in RNA polymerase I/III complexes. Validated in HeLa, MCF7, A-549, SW480, Jurkat. Supplied as liquid, affinity purified, 4.71 mg/mL, stored at -20°C.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–133 of human POLR1D (NP_057056.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.71 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914742 |
Product Specific Information
- Positive test controls: HeLa, MCF7, A-549, SW480, Jurkat
- Subcellular localization: Nucleus
Immunogen sequence:
MEEDQELERK ISGLKTSMAE GERKTALEMV QAAGTDRHCV TFVLHEEDHT LGNSLRYMIM KNPEVEFCGY TTTHPSESKI NLRIQTRGTL PAVEPFQRGL NELMNVCQHV LDKFEASIKD YKDQKASRNE STF
Target Information
The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are associated with Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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