Thermo Fisher Scientific FLASH Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues A(19) S P L K N N D E G S L D(31) of mouse FLASH. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FLASH,uniProtId:Q9WUF3-1,ncbiNodeId:10090,antigenRange:19-31|20-31,antigenLength:1962,antigenImageFileName:PA1-4167_FLASH_Q9WUF3-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4167_FLASH_Q9WUF3-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2068768

Product Specific Information

PA1-4167 detects the FLASH protein in Human, rat, and mouse samples.

PA1-4167 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~212 kDa protein representing FLASH in NIH3T3 cells.

The PA1-4167 immunogen is a synthetic peptide corresponding to residues A(19) S P L K N N D E G S L D(31) of mouse FLASH.

Maintain at 4ºC for 3 months or at -20ºC for longer periods. Stable for 1 year. Avoid repeated freeze/thaw cycles.

Target Information

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.