Thermo Fisher Scientific FLASH Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 1:500–1:1,000

Product Specifications

Product Specific Information

• PA1-4167 detects the FLASH protein in human, rat, and mouse samples.
• Successfully used in Western blot procedures.
• Detects a ~212 kDa protein representing FLASH in NIH3T3 cells.
• Immunogen: synthetic peptide corresponding to residues A(19) S P L K N N D E G S L D(31) of mouse FLASH.
• Recommended storage: 4°C for up to 3 months or -20°C for long-term. Stable for 1 year. Avoid repeated freeze/thaw cycles.

Target Information

FLASH is a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. It may be a component of the death-inducing signaling complex including Fas receptor, FADD, and caspase 8, playing a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.