Thermo Fisher Scientific DAP3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1–2 µg/mL

Product Specifications

Product Specific Information

• Suggested positive control: Jurkat, antigen standard for DAP3 (transient overexpression lysate), Jurkat whole cell lysate.

Target Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and assist in mitochondrial protein synthesis. Mitoribosomes consist of a small 28S subunit and a large 39S subunit, with a higher protein-to-rRNA ratio (approximately 75%) compared to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The protein encoded by this gene is part of the 28S subunit and is involved in apoptotic pathways initiated by TNF-α, Fas ligand, and IFN-γ. It may bind ATP/GTP and interact functionally with mitoribosomal protein S27. Splice variants differing in the 5′ UTR encode the same protein. Pseudogenes are located on chromosomes 1q and 2q.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.