Thermo Fisher Scientific Human Bcl-B Synthetic Peptide
인간 Bcl-B 단백질의 중심부 서열을 기반으로 한 합성 펩타이드입니다. 항체 차단 실험에 사용 가능하며, BCL-2 패밀리 단백질 연구에 적합합니다. 정제된 액상 형태로 제공되며, PBS 버퍼에 0.1% BSA와 0.02% sodium azide가 포함되어 있습니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the center of human LSD1.
PEP-0353 can be used as a blocking peptide with polyclonal antibody PA5-20234.
Target Information
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. The protein contains conserved BH4, BH1, and BH2 domains and interacts with other BCL-2 family members including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene can suppress apoptosis by preventing cytochrome C release from mitochondria, thereby inhibiting caspase-3 activation. In mouse, the homolog interacts with Apaf1 and forms a complex with Caspase 9, suggesting involvement in the APAF1 and CASPASE 9 apoptotic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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