Thermo Fisher Scientific Human TNFRSF14 Synthetic Peptide
Human TNFRSF14 단백질의 C-말단 16 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20236의 차단 펩타이드로 사용 가능. HSV 진입 및 면역 반응 연구용으로 적합. 연구용 시약으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human TNFRSF14.
PEP-0355 can be used as a blocking peptide with polyclonal antibody PA5-20236.
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily. It acts as a cellular mediator of herpes simplex virus (HSV) entry through binding of HSV envelope glycoprotein D (gD). The cytoplasmic region of TNFRSF14 interacts with TRAF family members, mediating signal transduction pathways that activate immune responses.
Activation of TNFRSF14 signaling in T cells promotes T cell proliferation and cytokine production, contributing to inflammation and CTL-mediated tumor immunity. Multiple alternatively spliced transcript variants have been described, though some full-length forms remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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