Thermo Fisher Scientific NGF-Receptor (p75)/CD271 (Soft Tissue Tumor Marker) Monoclonal Antibody (SPM299)
신경 성장 인자 수용체(NGFR/CD271)를 인식하는 단클론 항체로, 신경계 및 연조직 종양 연구에 적합. 다양한 종에서 반응하며 Mouse/Rat에는 반응하지 않음. IHC, ICC, Flow Cytometry 등 여러 응용에 사용 가능. 단백질 A/G로 정제된 액상 형태.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Cat, Ferret, Human, Non-human primate, Rabbit |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM299 |
| Immunogen | NGFR from A875 melanoma cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
Does not react with Mouse or Rat.
Target Information
Neurotrophic factors control the survival, differentiation, and maintenance of neurons in both the peripheral and central nervous systems, as well as other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo.
Antibodies that specifically react with NGFR p75 are valuable tools for detecting and characterizing NGFR p75, aiding in the understanding of neural development, plasticity, and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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