Thermo Fisher Scientific NGF-Receptor (p75)/CD271 (Soft Tissue Tumor Marker) Monoclonal Antibody (SPM299)
NGFR(p75)/CD271 단클론 항체(SPM299)는 신경 성장 인자 수용체 검출용으로 개발된 항체로, 인체 및 다양한 종에 반응합니다. IHC, ICC, Flow Cytometry 등 다중 응용 가능하며, 단백질 A/G로 정제된 고순도 제품입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Cat, Ferret, Human, Non-human primate, Rabbit |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM299 |
| Immunogen | NGFR from A875 melanoma cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Does not react with Mouse or Rat.
Target Information
Neurotrophic factors control the survival, differentiation, and maintenance of neurons in the peripheral and central nervous systems, as well as other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, enhancing our understanding of development, plasticity, and repair mechanisms in the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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