Thermo Fisher Scientific PRMT6 Monoclonal Antibody (PCRP-PRMT6-2C9)
인간 PRMT6 단백질을 인식하는 단클론 항체로, Flow Cytometry 및 Peptide Array에 사용 가능. 마우스 IgG2b 아이소타입이며, 단백질 A/G로 정제된 액상 형태. 4°C에서 보관하며 연구용으로만 사용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/10⁶ cells
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-PRMT6-2C9 |
| Immunogen | Recombinant full-length human PRMT6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
This antibody is predicted to react with Rat.
Target Information
Protein arginine N-methyltransferase 6 (PRMT6)
PRMT6 demonstrates type I PRMT activity, capable of forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on recombinant glycine- and arginine-rich substrates.
Acts as a transcriptional coactivator of several steroid hormone receptors including ESR1, ESR2, PGR, and NR3C1.
Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator.
May play a role in innate immunity against HIV-1 by methylating and impairing the function of various HIV-1 proteins such as Tat, Rev, and Nucleocapsid protein p7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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