Thermo Fisher Scientific PRMT6 Monoclonal Antibody (PCRP-PRMT6-2C9)
PRMT6 단백질을 인식하는 Mouse IgG2b 단일클론 항체로 인간 시료에 반응합니다. Flow Cytometry와 Peptide Array에 사용 가능하며, 단백질 A/G로 정제된 액상 형태입니다. 보존제가 없으며 -20°C 이하에서 보관합니다. 연구용으로만 사용됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/10^6 cells
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-PRMT6-2C9 |
| Immunogen | Recombinant full-length human PRMT6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
This antibody is predicted to react with Rat.
Target Information
Protein arginine N-methyltransferase 6 (PRMT6) demonstrates type I PRMT activity, forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on recombinant glycine- and arginine-rich substrates.
Acts as a transcriptional coactivator of steroid hormone receptors including ESR1, ESR2, PGR, and NR3C1.
Promotes fasting-induced transcriptional activation of the gluconeogenic program via methylation of the CRTC2 transcription coactivator.
May play a role in innate immunity against HIV-1 by methylating and impairing the function of viral proteins such as Tat, Rev, and Nucleocapsid protein p7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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