Thermo Fisher Scientific Human HAX1 alpha Synthetic Peptide
인간 HAX1 알파 서열 기반 합성 펩타이드로, PA5-20649 항체의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태이며 PBS 버퍼에 보존. 연구용으로만 사용되며 진단용 불가.
- 카탈로그번호
- PEP0769
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the amino terminus of human Hax1 isoform a.
PEP-0769 can be used as a blocking peptide with polyclonal antibody PA5-20649.
Target Information
The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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