Thermo Fisher Scientific CDKN2B Monoclonal Antibody (DCS114.1)
CDKN2B 단백질을 표적으로 하는 Thermo Fisher Scientific의 DCS114.1 단일클론 항체. Western blot, IHC, ICC, IP 등 다양한 응용 가능. 인간 반응성, 마우스 IgG1 형식, 액상 형태로 제공. 연구용으로만 사용.
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- pk
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Thermo Fisher Scientific CDKN2B Monoclonal Antibody (DCS114.1)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–5 µg/mL | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–5 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| Immunoprecipitation (IP) | 1–5 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Gerbil, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DCS114.1 |
| Immunogen | His-tagged recombinant full length p15 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073568 |
Target Information
The four known 15–19 kDa INK4 proteins (p15INK4b, p16INK4a, p18INK4c, and p19INK4d) bind and inhibit CDK4 and CDK6 but not other CDKs, including cyclin E-Cdk2, cyclin A-Cdk2, and cyclin B-Cdk1. Like the three D-type cyclins, the INK4 genes are expressed in distinct tissue-specific patterns, suggesting that they are not strictly redundant. p18INK4c is expressed during G1 to S transition in the eukaryotic cell division cycle and is maximally induced as cells enter S-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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