Thermo Fisher Scientific ASB2 Monoclonal Antibody (OTI2A2), TrueMAB
ASB2 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, IHC(P)에서 1:150 희석으로 검증됨. Human, Mouse, Rat에 반응하며, PBS 기반 저장 버퍼와 동결건조 형태로 제공. 연구용 단백질 검출 및 결합 실험에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-300 of human ASB2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
- For conjugation experiments using carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ASB2 protein is a member of the ankyrin repeat and SOCS box-containing (ASB) family. It includes ankyrin repeat sequences and a SOCS box domain that couples SOCS proteins with elongin B and C complexes, potentially targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, ASB2 expression induces growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been reported, though their full-length sequences are not fully known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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