Thermo Fisher Scientific Thimet Oligopeptidase Monoclonal Antibody (4D6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:750-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:400

-

Immunocytochemistry (ICC/IF)

1:10-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rabbit, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

4D6

Immunogen

Synthetic peptide corresponding to residues 56-72 of human THOP1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Thimet Oligopeptidase,uniProtId:P52888-1,ncbiNodeId:9606,antigenRange:56-72,antigenLength:689,antigenImageFileName:MA5-24783_Thimet_Oligopeptidase_P52888-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24783_Thimet_Oligopeptidase_P52888-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.54 mg/mL

Purification

Protein A

Storage buffer

TBS

Contains

0.05% sodium azide

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_2717256

Target Information

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.