Thermo Fisher Scientific Gephyrin Polyclonal Antibody
Gephyrin 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며 합성 펩타이드를 면역원으로 사용했습니다. 동결건조 형태로 제공되며, 4°C 또는 -20°C에서 보관 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal of human Gephyrin (GPHN) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Gephyrin.
Target Information
Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to receptor subunit domains and tubulin dimers.
In non-neuronal tissues, this protein is also required for molybdenum cofactor biosynthesis.
Mutations in this gene may be associated with hyperplexia and molybdenum cofactor deficiency.
Multiple alternatively spliced transcript variants encoding different isoforms have been described, though not all are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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