Thermo Fisher Scientific Phospho-ATR (Ser428) Recombinant Rabbit Monoclonal Antibody (7F9W10)
세린/트레오닌 키나제 ATR의 인산화 형태(Ser428)를 검출하는 재조합 토끼 모노클로날 항체. Western blot 및 ELISA에 적합하며 높은 특이성과 재현성을 제공. 인간 시료 반응성, 액상 형태로 안정적 저장 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7F9W10 |
| Immunogen | A synthetic phosphorylated peptide around S428 of human ATR (NP_001175.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.215 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093093 |
Product Specific Information
- Immunogen sequence: GISPK
Target Information
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress.
It phosphorylates and activates several proteins involved in the inhibition of DNA replication and mitosis, and promotes DNA repair, recombination, and apoptosis.
This protein is also important for fragile site stability and centrosome duplication.
Defects in this gene are a cause of Seckel syndrome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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