Thermo Fisher Scientific PKM1/PKM2 Monoclonal Antibody (F.313.7)
PKM1/PKM2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot, ICC/IF, IP에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 연구용 적합.
- 카탈로그번호
- MA514815
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific PKM1/PKM2 Monoclonal Antibody (F.313.7)
Applications and Tested Dilution
- Western Blot (WB): 1:1,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
- Immunoprecipitation (IP): 2–5 µL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F.313.7 |
| Immunogen | Synthetic peptide corresponding to the sequence of human PKM1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 43 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_11005173 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate.
This protein interacts with thyroid hormone and may mediate metabolic effects induced by thyroid hormones. It also binds Opa protein, a bacterial outer membrane protein involved in gonococcal adherence and invasion of human cells, suggesting a role in bacterial pathogenesis.
Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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