Thermo Fisher Scientific CD1C Monoclonal Antibody (UMAB46), UltraMAB
인간 CD1C 단백질을 표적하는 마우스 모노클로날 항체로, Western blot, IHC, ChIP 등 다양한 응용 가능. 고순도 친화 크로마토그래피 정제, 동결건조 형태. PBS + 8% 트레할로스 버퍼, -20°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | Assay-dependent | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | |
| ChIP assay (ChIP) | Assay-dependent | |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB46 |
| Immunogen | Full length human recombinant protein of human CD1C produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a member of the CD1 family of transmembrane glycoproteins, structurally related to MHC proteins. CD1 proteins form heterodimers with beta-2-microglobulin and present lipid and glycolipid antigens to T cells.
The human genome contains five CD1 family genes organized on chromosome 1. CD1 family members differ in localization and lipid ligand specificity.
The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail and requires vesicular acidification for lipid antigen binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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