Thermo Fisher Scientific CD1C Monoclonal Antibody (UMAB46), UltraMAB
인간 CD1C 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western Blot, IHC, ChIP 등에 사용 가능. HEK293T 세포에서 생산된 재조합 단백질을 면역원으로 사용. 액상 형태이며 PBS/BSA/glycerol 완충액에 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Dilution: 1:100
ChIP assay (ChIP)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB46 |
| Immunogen | Full length human recombinant protein of human CD1C produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.
CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.
The human genome contains five CD1 family genes organized in a cluster on chromosome 1.
CD1 family members differ in their cellular localization and specificity for particular lipid ligands.
The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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