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Thermo Fisher Scientific Crk Polyclonal Antibody
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Human 및 Mouse 시료에 반응하는 Rabbit Polyclonal Anti-Crk 항체. Western blot 및 ELISA에 적합하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며 -20°C에서 장기 보관 가능. 연구용으로만 사용.
- 카탈로그번호
- PA5116651
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오후 09:47
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Thermo Fisher Scientific PA5116651 Crk Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
655,000원VAT 포함 720,500원
Thermo Fisher Scientific · Thermo Fisher Scientific Crk Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–304 of human CRK/CRKII (NP_0584312) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.18 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901282 |
Product Specific Information
- Positive Samples: A-549, MCF7, BT-474, Mouse brain
- Immunogen sequence:
MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL LEFYKIHYLD TTTLIEPVSR SRQGSGVILR QEEAEYVRAL FDFNGNDEED LPFKKGDILR IRDKPEEQWW NAEDSEGKRG MIPVPYVEKY RPASASVSAL IGGNQEGSHP QPLGGPEPGP YAQPSVNTPL PNLQNGPIYA RVIQKRVPNA YDKTALALEV GELVKVTKIN VSGQWEGECN GKRGHFPFTH VRLLDQQNPD EDFS
Target Information
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling, and cell motility in a Rac-dependent manner. It is involved in phagocytosis of apoptotic cells and cell motility via interaction with DOCK1 and DOCK4, and may regulate EFNA5–EPHA3 signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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