Thermo Fisher Scientific Growth Hormone Monoclonal Antibody (KT19)
인간 성장호르몬(hGH)을 인식하는 Rat IgG1 단일클론 항체(KT19). IHC(P) 및 ELISA에 사용 가능하며, 비결합형 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| ELISA | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KT19 |
| Immunogen | Recombinant Human GH1 (aa 61–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090643 |
Product Specific Information
This product was used in both Indirect and Sandwich ELISA.
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with four additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.
HGH is produced by the somatotroph cells in the pituitary and acts through binding to membrane receptors belonging to the cytokine receptor subfamily. Its major role in stimulating body growth is to promote the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts, as well as amino acid uptake and protein synthesis in muscle and other tissues.
Mutations or deletions in the gene lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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