Thermo Fisher Scientific Lactoferrin Monoclonal Antibody (KT14)

Applications

• ELISA (ELISA): Tested dilution 1:200
  • 본 제품은 Indirect 및 Sandwich ELISA에 사용되었습니다.

Product Specifications

Product Specific Information

This product was used in both Indirect and Sandwich ELISA.

Target Information

Lactoferrin (LF) is an iron-binding glycoprotein composed of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺). It is present in external fluids such as milk and mucosal secretions and is a major component of neutrophil secondary granules.
LF exhibits diverse biological activities, including:

• Regulation of iron homeostasis
• Defense against microbial infections
• Anti-inflammatory activity
• Regulation of cellular growth and differentiation
• Protection against cancer development and metastasis

Lactoferrin functions as a first line of defense against microbial infection through iron sequestration and direct bactericidal activity. It can cleave arginine-rich sequences in microbial proteins.
Three isoforms (LTF-α, LTF-β, LTF-γ) are known, and receptors for LTF are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and some bacteria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.