Thermo Fisher Scientific CRHR1 Recombinant Superclonal Antibody (4HCLC)

Applications

Western Blot (WB)

• Tested Dilution: 1 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Dog, Pig, Rabbit.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds — the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies — all delivered with the consistency only found in a recombinant antibody.

While functionally the same as a polyclonal antibody — recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets — a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.

Target Information

Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors. Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease. Multiple isoforms of CRFR1 are produced by alternative splicing.

CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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