Thermo Fisher Scientific AGR2 Recombinant Rabbit Monoclonal Antibody (HL1024)
AGR2 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며, HEK293 세포에서 발현된 재조합 항체입니다. Protein A로 정제된 액상형 제품으로 장기 보관 시 -20°C 이하에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | — |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | — |
| Immunocytochemistry (ICC/IF) | Assay-dependent | — |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL1024 |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Anterior Gradient 2 (AGR2). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911491 |
Product Specific Information
- Store as a concentrated solution.
- Centrifuge briefly prior to opening vial.
- For short-term storage (1–2 weeks), store at 4°C.
- For long-term storage, aliquot and store at -20°C or below.
- Avoid multiple freeze-thaw cycles.
Target Information
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins involved in metastasis induction and p53 tumor suppressor inhibition. AGR2 may serve as a molecular marker and potential therapeutic target for hormone-responsive breast tumors. It is ubiquitously expressed and upregulated in prostate, breast, lung, renal, and endometrial carcinomas. AGR2 expression is positively correlated with estrogen receptor (ER) and negatively correlated with epidermal growth factor receptor (EGFR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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