Thermo Fisher Scientific Zika Virus NS1 Monoclonal Antibody (GT5212)
Thermo Fisher Scientific의 Zika Virus NS1 단백질을 타겟으로 하는 단클론 항체입니다. Western blot, ICC/IF, ELISA에 적합하며 고순도 Protein G 정제 제품입니다. 장기 보관 시 -20°C 이하에서 안정적으로 유지됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| ELISA | 1:1,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT5212 |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Zika virus NS1 protein (Zika virus strain H/PF/2013). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911488 |
Product Specific Information
- Store as concentrated solution.
- Centrifuge briefly prior to opening vial.
- For short-term storage (1–2 weeks), store at 4°C.
- For long-term storage, aliquot and store at -20°C or below.
- Avoid multiple freeze-thaw cycles.
Target Information
Zika virus (ZIKV), a member of the Flaviviridae family, possesses a single positive-sense RNA genome that is translated as a polyprotein, subsequently cleaved into three structural proteins (C, PrM/M, and E) and seven nonstructural (NS) proteins (NS1–NS5).
The glycosylated NS1 forms intracellular homodimers essential for viral replication and is secreted as a hexameric lipoprotein particle. This secreted form aids immune evasion and pathogenesis by interacting with components of both innate and adaptive immune systems.
References:
- Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F. (2016). Nat. Struct. Mol. Biol. 23, 456–458.
- Suthar, M.S.; Diamond, M.S.; Gale, M. Jr. (2013). Nat. Rev. Microbiol. 11, 115–128.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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