Thermo Fisher Scientific Insulinoma Associated 2/INSM2 Monoclonal Antibody (INSM2, 4291)
인간 INSM2 단백질을 인식하는 Mouse IgG1 단클론 항체. IHC(P) 및 Peptide Array에 사용 가능. 단백질 A/G 정제 및 PBS 버퍼에 보관. 4°C에서 안정적이며 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | INSM2, 4291 |
| Immunogen | Recombinant fragment of human INSM2 protein (around aa 432–540) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
IA-6, also known as insulinoma-associated 2 (INSM2), is related to IA-1 (INSM1), a zinc-finger factor expressed in the developing nervous system.
While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes.
The homology exhibited by IA-6 to IA-1 suggests that IA-6 may also play a role in the regulation of gene transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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