Thermo Fisher Scientific Insulinoma Associated 2/INSM2 Monoclonal Antibody (INSM2, 4291)
INSM2 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody. 인간 시료에 반응하며 IHC 및 Peptide Array에 적용 가능. 고순도 Protein A/G 정제, 액상 형태, 보존제 무첨가. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | INSM2, 4291 |
| Immunogen | Recombinant fragment of human INSM2 protein (around aa 432–540) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
IA-6 (Insulinoma-associated 2, INSM2) is related to IA-1 (INSM1), a zinc-finger factor expressed in the developing nervous system.
While the exact function of IA-6 is not known, related proteins such as IA-2 are major autoantigens in type 1 diabetes.
The homology between IA-6 and IA-1 suggests that IA-6 may play a role in gene transcription regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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