Thermo Fisher Scientific Acetylcholinesterase Polyclonal Antibody
Acetylcholinesterase 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 polyclonal 항체. Western blot, ICC/IF, Flow cytometry에 사용 가능. 인간 반응성, 다른 종에 예측 반응. TBS buffer에 0.5 mg/mL 농도로 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QFDHYSKQDRCSDL) corresponding to the C-terminus amino acids of ACHE (aa 601–614) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11000727 |
Product Specific Information
- This antibody is predicted to react with bovine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
Acetylcholinesterase hydrolyzes the neurotransmitter acetylcholine at neuromuscular junctions and brain cholinergic synapses, thereby terminating signal transmission. The protein is also found on red blood cell membranes, where it constitutes the Yt blood group antigen.
Acetylcholinesterase exists in multiple molecular forms with similar catalytic properties but differing in oligomeric assembly and mode of cell surface attachment. The major form found in brain, muscle, and other tissues is hydrophilic, forming disulfide-linked oligomers with collagenous or lipid-containing structural subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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