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Thermo Fisher Scientific MB21D1 Monoclonal Antibody (7E3)
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Thermo Fisher Scientific MB21D1 Monoclonal Antibody (7E3)

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인간 MB21D1(cGAS) 단백질을 인식하는 마우스 모노클로날 항체로 Western blot에 적합. KLH 결합 합성 펩타이드로 면역화하여 제작. 단백질 G로 정제된 액상 항체이며, TBS 버퍼(40% glycerol, 1% BSA) 내 저장. 연구용으로만 사용 가능.

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마지막 업데이트 2025. 08. 05. 오후 08:10
Thermo Fisher Scientific BSM-51379M MB21D1 Monoclonal Antibody (7E3) 100 ul pk판매 단위 pk ·
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527,900원VAT 포함 580,690원

Thermo Fisher Scientific · Thermo Fisher Scientific MB21D1 Monoclonal Antibody (7E3)

Thermo Fisher Scientific MB21D1 Monoclonal Antibody (7E3)

Applications

  • Western Blot (WB)

Tested Dilution

  • 1:4,000

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG1, kappa
Class Monoclonal
Type Antibody
Clone 7E3
Immunogen Mouse immunized with a KLH-conjugated synthetic peptide (amino acids 1–185 from human MB21D1)
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Purification Protein G
Storage Buffer TBS, pH 7.4, with 40% glycerol, 1% BSA
Contains 0.02% ProClin 300
Storage Conditions -20°C
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

cGAS (Cyclic GMP-AMP synthase) is a nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP, playing a key role in innate immunity. It binds cytosolic DNA directly, leading to activation and synthesis of cGAMP, which subsequently activates TMEM173/STING to trigger type-I interferon production. cGAS is involved in innate immune sensing of infection, detection of bacterial DNA, response to cellular stress, DNA damage, and regulation of cellular senescence.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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