Thermo Fisher Scientific SRC Monoclonal Antibody (2C2)
SRC 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 최적화됨. Human SRC에 반응하며 Protein G로 정제된 액상 형태. TBS buffer에 40% glycerol, 1% BSA 포함, -20°C 보관. 세포 성장 및 신호전달 연구용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C2 |
| Immunogen | This SRC antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1–350 amino acids from human SRC. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | TBS with 40% glycerol, 1% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth. It associates with the cytoplasmic region of various cell surface receptors to facilitate signal transduction and is involved in cytoskeletal organization, cell cycle regulation, and apoptosis.
In humans, the SRC gene is located on chromosome 20. Activity is regulated by phosphorylation at Tyr416 and Tyr527, which have opposing effects on enzyme activity. Mutations in SRC may contribute to malignant progression of colon cancer. Two transcript variants encoding the same SRC protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: BSM-51358M_SRC_P12931-1_House_mouse.svg, BSM-51358M_SRC_P12931-1_House_mouse_PDP.jpeg)
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