Thermo Fisher Scientific MVP Polyclonal Antibody
MVP 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 적용 가능. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상 제품이며, PBS/50% glycerol buffer에 보관. 약물 저항성 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MVP (Accession Q14764), corresponding to amino acid residues M1–A46 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900239 |
Product Specific Information
Antibody detects endogenous levels of total MVP.
Target Information
This gene encodes the major vault protein (MVP), which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, possibly via a transport process. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells. Overexpression of this protein is a potentially useful marker of clinical drug resistance.
This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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