Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI2D5), TrueMAB
인간 LIPG 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot, IHC, ICC, Flow cytometry, IP 등 다양한 응용에 사용 가능. HEK293T 세포에서 발현된 full-length LIPG 항원을 면역원으로 사용. 고순도 친화 크로마토그래피 정제 및 안정적 PBS/BSA/glycerol 저장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D5 |
| Immunogen | Full length human recombinant protein of human LIPG produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions locally at the site of synthesis.
LIPG plays a physiological role in modulating lipoprotein metabolism. Overexpression of LIPG reduces HDL cholesterol levels, while LIPG deficiency elevates HDL cholesterol in animal models.
It exhibits substantial phospholipase activity and contributes to lipoprotein metabolism and vascular biology.
LIPG is part of the TG lipase family, characterized by a lid region that provides substrate specificity. It acts as a carboxyl esterase that hydrolyzes HDL, emulsifies triglycerides, and assists in dietary fat digestion, with heparin-binding capability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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