Thermo Fisher Scientific GDNF Polyclonal Antibody
GDNF 단백질을 인식하는 sheep 유래 polyclonal antibody로, 인간·생쥐·랫트 반응성 보유. Western blot에 적합하며, recombinant human GDNF(aa78–211)를 면역원으로 사용. Lyophilized 형태로 제공되며 PBS buffer에 보존, -20°C에서 안정적 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
- Publications: N/A
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human GDNF (aa 78–211) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074599 |
Product Specific Information
Reconstitute in 50 µL of sterile water. Centrifuge to remove any insoluble material. After reconstitution, keep aliquots at -20°C for higher stability, or at 4°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Target Information
GDNF (Glial cell line-derived neurotrophic factor) is a glycosylated, disulfide-bonded homodimer molecule. It was first identified as a potent survival factor for midbrain dopaminergic neurons and shown to rescue these neurons in animal models of Parkinson’s disease. GDNF is approximately 100 times more effective as a survival factor for spinal motor neurons than neurotrophins. It promotes survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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