Thermo Fisher Scientific CHP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

ChIP assay (ChIP)

2.5 µg for 10^7 cells

-

Product Specifications

Species Reactivity

Yeast

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 900 to the C-terminus of Schizosaccharomyces pombe Chp1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHP1,uniProtId:Q10103-1,ncbiNodeId:-23,antigenRange:90-960|900-960,antigenLength:960,antigenImageFileName:PA5-34611_CHP1_Q10103-1_Rabbit.svg,antigenImageFileNamePDP:PA5-34611_CHP1_Q10103-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 1% BSA

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2551963

Product Specific Information

PA5-34611 targets Chp1 in ChIP and WB applications and shows reactivity with Yeast samples.

The PA5-34611 immunogen is synthetic peptide conjugated to KLH derived from within residues 900 to the C-terminus of Schizosaccharomyces pombe Chp1.

PA5-34611 detects Chp1 which has a predicted molecular weight of approximately 109 kDa.

Target Information

Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.