Thermo Fisher Scientific UBE2A Polyclonal Antibody
Rabbit polyclonal antibody targeting UBE2A (Human Rad6) for WB, IHC, and ICC applications. Unconjugated, liquid form with 0.5 mg/mL concentration. Suitable for multiple species based on sequence homology. Optimized for research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from residues 1–100 of Human Rad6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551967 |
Product Specific Information
- Heat-mediated antigen retrieval recommended prior to tissue staining.
- Immunohistochemistry has been successfully performed with methylmethacrylate sections.
- Predicted to react with rabbit, chicken, cow, Saccharomyces cerevisiae, Xenopus laevis, and fruit fly (Drosophila melanogaster) based on sequence homology.
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s).
This gene encodes a member of the E2 ubiquitin-conjugating enzyme family, required for post-replicative DNA damage repair. Multiple alternatively spliced transcript variants encode distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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