Thermo Fisher Scientific CEACAM1 Monoclonal Antibody (GM8G5)
인간 CEACAM1 단백질을 인식하는 GM8G5 클론의 마우스 단클론 항체. IHC, Flow cytometry, ELISA 등 다양한 응용 가능. 비결합형 액상 형태로 제공되며 2 mg/mL 농도. 연구용으로만 사용.
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Thermo Fisher Scientific CEACAM1 Monoclonal Antibody (GM8G5)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | 10 µg/mL |
| Flow Cytometry (Flow) | 1.2 µg/1x10^6 cells |
| ELISA | 1:200 - 1:400 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GM8G5 |
| Immunogen | cDNA encoding the extracellular region of human CEACAM1-A2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1073289 |
Product Specific Information
This antibody recognizes native human CEACAM1 protein expressed in transfected mammalian cells.
Target Information
CEACAM1 is a member of the carcinoembryonic antigen (CEA) gene family within the immunoglobulin superfamily. The CEA family includes cell adhesion molecules and pregnancy-specific glycoproteins located in a 1.2 Mb cluster on chromosome 19. CEACAM1 was initially identified in liver bile ducts and later found on leukocytes, epithelial, and endothelial cells. It mediates cell adhesion through homophilic and heterophilic interactions and plays roles in tissue organization, angiogenesis, apoptosis, tumor suppression, metastasis, and immune response modulation. Multiple transcript variants exist, with two full-length isoforms characterized.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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