Thermo Fisher Scientific SLC26A2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:2,500-1:5,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SLC26A2. Recombinant protein control fragment (Product #RP-103884). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC26A2,uniProtId:P50443-1,ncbiNodeId:9606,antigenRange:4-82,antigenLength:739,antigenImageFileName:PA5-63524_SLC26A2_P50443-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63524_SLC26A2_P50443-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647426

Product Specific Information

Immunogen sequence: ESKEQHNVSP RDSAEGNDSY PSGIHLELQR ESSTDFKQFE TNDQCRPYHR ILIERQEKSD TNFKEFVIKK LQKNCQCSP

Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 51%.

Target Information

The SLC26 family is comprised of sulfate/anion transporters that are well conserved in both their genomic and protein structures, yet have markedly different tissue expression patterns. Members of the SLC26 family can mediate the electroneutral exchange of Cl- for HCO3- across the plasma membrane of mammalian cells. SLC26A2 (solute carrier family 26, member 2), also known as DTD, EDM4, DTDST, MST153, D5S1708 or MSTP157, is a 739 amino acid diastrophic dysplasia sulfate transporter belonging to the SLC26A/SulP transporter family. Ubiquitously expressed, SLC26A2 may play a role in endochondral bone formation. SLC26A2 is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias and is critical for sulfation of proteoglycans and matrix organization in cartilage.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.