Thermo Fisher Scientific SH3RF2 Polyclonal Antibody
Human SH3RF2 단백질에 특이적인 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보존. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SH3RF2. Recombinant protein control fragment (Product #RP-103317). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647253 |
Product Specific Information
Immunogen sequence:
QGSLRKGRSS MRKNGSLQRP LQSGIPTLVV GSLRRSPTMV LRPQQFQFYQ PQGIPSSPSA VVVEMGSKPA LTGEPALTCI SRGSE
- Highest antigen sequence identity to the following orthologs:
- Mouse: 76%
- Rat: 74%
Target Information
The SH3RF2 gene encodes a protein with protein phosphatase 1 binding activity and ubiquitin protein ligase activity.
It is involved in:
- Positive regulation of the JNK cascade
- Protein autoubiquitination
- Regulation of cellular protein metabolic processes
The protein is located in the nucleoplasm, and mutations in the SH3RF2 gene have been associated with Ureter Transitional Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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