Thermo Fisher Scientific Prostein Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptides corresponding to residues I(36) T Y V P P L L L E V G V E E(50) and F(537) A T Q V V F D K S D L A K Y S A(553) of human Prostein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Prostein,uniProtId:Q96JT2-1,ncbiNodeId:9606,antigenRange:36-50|537-553,antigenLength:553,antigenImageFileName:PA1-4230_Prostein_Q96JT2-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4230_Prostein_Q96JT2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2191100

Product Specific Information

PA1-4230 detects the Prostein protein in human samples.

PA1-4230 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~55 kDa protein representing Prostein in metastatic adenocarcinoma LNCaP.FGC cells.

PA1-4230 immunogen is a mixture of synthetic peptides corresponding to the N- and C-terminal residues I(36) T Y V P P L L L E V G V E E(50) and F(537) A T Q V V F D K S D L A K Y S A(553) of human Prostein.

Target Information

Prostein is a novel prostate-specific protein expressed in normal and malignant prostate tissues. This protein appears to be a type IIIa plasma membrane protein with a cleavable signal peptide and 11 transmembrane-spanning regions. Prostein expression is androgen responsive since treatment of LNCaP cells with androgen up-regulates prostein message and protein expression levels. Thus, prostein is a prostate-specific marker whose detection and quantitation may be useful in diagnosing and monitoring prostate cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.