Thermo Fisher Scientific Prostein Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500
• Publications: 없음

Product Specifications

Product Specific Information

• PA1-4230 detects the Prostein protein in human samples.
• Successfully used in Western blot procedures.
• Detects a ~55 kDa protein representing Prostein in metastatic adenocarcinoma LNCaP.FGC cells.
• Immunogen is a mixture of synthetic peptides corresponding to the N- and C-terminal residues I(36) T Y V P P L L L E V G V E E(50) and F(537) A T Q V V F D K S D L A K Y S A(553) of human Prostein.

Target Information

Prostein is a novel prostate-specific protein expressed in normal and malignant prostate tissues.
This protein appears to be a type IIIa plasma membrane protein with a cleavable signal peptide and 11 transmembrane-spanning regions.
Prostein expression is androgen responsive since treatment of LNCaP cells with androgen up-regulates prostein message and protein expression levels.
Thus, Prostein is a prostate-specific marker whose detection and quantitation may be useful in diagnosing and monitoring prostate cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.