Thermo Fisher Scientific COLQ Polyclonal Antibody
Human COLQ 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. HepG2 세포 양성 대조군 권장, Mouse·Rat·Bovine에서 예측 반응성을 보입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 248–455 of Human COLQ |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548415 |
Product Specific Information
- Recommended positive controls: HepG2
- Predicted reactivity: Mouse (87%), Rat (82%), Bovine (87%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase) is a 455 amino acid protein localized at the skeletal muscle end plate. It anchors catalytic subunits of asymmetric AChE to the basal lamina at vertebrate neuromuscular junctions.
Mutations in COLQ cause congenital myasthenic syndromes, rare autosomal recessive diseases characterized by muscle weakness, ophthalmoplegia, and resistance to anticholinesterase drugs.
Eight isoforms exist due to alternative splicing.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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