Thermo Fisher Scientific MMP1 Monoclonal Antibody (6A5)
인간 MMP1 단백질을 인식하는 Mouse IgG1 단클론 항체로 다양한 응용 분야(WB, IHC, ICC/IF, Flow, ELISA)에 사용 가능. 비결합형 액상 형태이며 54kDa 크기의 MMP1 검출에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | - |
| Flow Cytometry (Flow) | 1:200–1:400 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6A5 |
| Immunogen | Purified recombinant fragment of human MMP1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154007 |
Product Specific Information
MA5-15872 targets MMP1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with human samples.
The MA5-15872 immunogen is a purified recombinant fragment of human MMP1 expressed in E. coli.
MA5-15872 detects MMP1, which has a predicted molecular weight of approximately 54 kDa.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes including arthritis and metastasis.
Most MMPs are secreted as inactive proproteins that are activated when cleaved by extracellular proteinases.
This gene encodes a secreted enzyme which breaks down interstitial collagens (types I, II, and III).
The gene is part of a cluster of MMP genes localized to chromosome 11q22.3.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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