Thermo Fisher Scientific Phospho-ILK (Ser246) Polyclonal Antibody
Human ILK 단백질의 Ser246 인산화 부위를 인식하는 rabbit polyclonal antibody. IHC(Paraffin) 실험에 적합하며, 고순도 affinity chromatography로 정제됨. PBS/glycerol buffer에 보관하며 -20°C에서 안정적 저장 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:100 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of Serine 246 (I-F-S(p)-H-P) derived from Human ILK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554217 |
Product Specific Information
A suggested positive control for IHC is human brain tissue.
Target Information
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions and requires interaction of integrin cytoplasmic domains with cellular proteins.
Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with four ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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