Thermo Fisher Scientific CCL2 (MCP-1) Monoclonal Antibody (4E2), eBioscience
마우스 MCP-1(CCL2)을 인식하는 단클론 항체로 ELISA 캡처용으로 검증됨. 아르메니아 햄스터 유래 IgG 항체이며 비결합형 액상 형태. SDS-PAGE 기준 90% 이상 순도, 0.5 mg/mL 농도. 4°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| ELISA (ELISA) | 1–4 µg/mL | View 3 publications |
| Neutralization (Neu) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Armenian hamster / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4E2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_468428 |
Product Specific Information
Description:
The 4E2/MCP antibody reacts with mouse monocyte chemoattractant protein-1 (MCP-1).
Applications Reported:
This 4E2 antibody has been reported for use in ELISA.
Applications Tested:
The 4E2 antibody has been tested as the capture antibody in a sandwich ELISA in combination with the Biotin 2H5 (Product # 13-7096-85) antibody for detection of mouse CCL2 (MCP-1, MCP1, MCAF).
A suitable range of concentrations of this antibody for ELISA capture is 1–4 µg/mL.
Purity: Greater than 90%, as determined by SDS-PAGE.
Aggregation: Less than 10%, as determined by HPLC.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are secreted proteins involved in immunoregulatory and inflammatory processes. The encoded protein is structurally related to the CXC subfamily of cytokines, characterized by two cysteines separated by a single amino acid.
This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in diseases with monocytic infiltrates such as psoriasis, rheumatoid arthritis, and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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