Thermo Fisher Scientific TARC Recombinant Rabbit Monoclonal Antibody (B22H33L5)

Applications

Western Blot (WB)

• Tested Dilution: 1–5 µg/mL

Immunohistochemistry (IHC)

• Tested Dilution: Not specified
• View 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:20

Product Specifications

Product Specific Information

• Intact IgG appears as a ~150 kDa band under non-reducing conditions, and upon reduction generates ~25 kDa light chain and ~50 kDa heavy chain bands.
• Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning antibody DNA sequences from immunoreactive rabbits.
• Advantages include:
  • Improved specificity and sensitivity
  • Lot-to-lot consistency
  • Animal origin-free formulation
  • Broader immunoreactivity due to larger rabbit immune repertoire

Target Information

TARC ligand (CCL17) is a member of the CC chemokine family. It is a small cytokine located on the q arm of chromosome 16 in humans, along with other chemokines.
TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8.
It plays a key role in T-cell development in the thymus and in trafficking and activation of mature T cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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