Thermo Fisher Scientific PPP2R1B Polyclonal Antibody
Rabbit polyclonal antibody targeting human PPP2R1B, suitable for WB, IHC(P), and ICC/IF. Detects endogenous 66 kDa protein with >95% purity. Unconjugated form, 1 mg/mL concentration, ideal for research use only.
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Thermo Fisher Scientific PPP2R1B Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:500–1:1,000
- Immunohistochemistry (Paraffin) [IHC(P)]: 1:50–1:200
- Immunocytochemistry (ICC/IF): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 556–601 of human PPP2R1B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553869 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 66 kDa.
Purity is >95% by SDS-PAGE.
Target Information
In eukaryotes, phosphorylation and dephosphorylation of proteins on serine and threonine residues regulate diverse cellular functions such as division, homeostasis, and apoptosis. Protein phosphatases, including PP1, PP2A, PP2B (calcineurin), and PP2C, play key roles in these processes.
PP2A holoenzyme is a trimeric complex composed of a regulatory, variable, and catalytic subunit. The PP2A family includes subfamily members PP2A alpha and PP2A beta. Regulatory subunits include PP2A-A alpha and -A beta, PP2A-B alpha and -B beta, PP2A-C alpha and -C beta, and PP2A-B56 alpha and -B56 beta.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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