Thermo Fisher Scientific GPBB Polyclonal Antibody
Thermo Fisher Scientific의 GPBB Polyclonal Antibody는 인간 및 비인간 영장류 시료에 반응하는 토끼 유래 IgG 항체입니다. IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 뇌 조직 내 glycogen phosphorylase 분석에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Application: Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 10 amino acid peptide from internal region of human PYGB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550472 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- 100%: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Elephant
- 90%: Mouse, Bat, Hamster, Opossum, Platypus
- 80%: Rat, Dog, Panda, Horse, Rabbit, Lizard, Salmon, Pufferfish, Zebrafish
For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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